5

DNAPrint Genomics to be Acquired by Nanobac Pharmaceuticals

DNAPrintG GenomeWeb Daily News announced on Friday that DNAPrint Genomics is being purchased by Nanobac Pharmaceuticals (I’ve written about DNAPrint here and here, including about their Doggie DNAPrint product). Here is the press release from Nanobac.

DNAPrint had a big year in 2007 with a number of partnerships and new products, and many people have forgotten or were unaware that the autosomal genetic genealogical tests offered by DNAPrint’s AncestrybyDNA are just a small part of the company’s business. From the Nanobac press release:

“DNAG’s primary objective has been, and Nanobac’s primary objective will be, to develop progressive theranostics drugs, which combine extensively modeled drugs with genomics-derived intelligence to create more economical and powerful drug/test combination products with superior performance parameters. DNAG’s flagship product, PT-401, is expected to result in more effective treatment of anemia, and its Protectin(TM) (CD-59) diagnostic test is expected to allow patients and their physicians to more effectively manage the risks and treatment decisions for diabetes. DNAG supports its clinical programs, in part, through the sale of consumer genetics tests genotyping services on a contractual basis.”

Will DNAPrint/Nanobac continue to offer and develop their autosomal DNA testing products in the face of startups like deCODEme, 23andMe, and SeqWright? I wonder if they’ve seen any decline in business since the launch of these companies. I think DNAPrint/Nanobac will have to implement … Click to read more!

10

African American Lives 2

AAL2 According to some sources, genetic genealogy testing rises considerably during February, which is Black History Month (as I wrote about last February). Part of this might be due to last year’s very popular TV show “African American Lives” on PBS. Starting next week (on the 6th) is the first half of the latest version of the show, “African American Lives 2.” I’ll be watching, and I think most of you will be interested in the show as well.

In anticipation of this series, Diverse Education has written an article entitled “The Value of Knowing Where You Come From.” The author of this article, Cassie Chew, recently interviewed me and a few of my quotes made it into the article. The article wonders if there is a possible genetic explanation for behaviors that run in families. For instance, one of … Click to read more!

11

Where Was My Y-DNA and mtDNA in 1808?

A few days ago I wrote about John Reid’s “Where Has Your DNA Been” post at Anglo-Connections a few days ago. This is similar to another meme which has been circulating the genealogy blogosphere for a few weeks now, including “Where was your family in 1908?” at 100 Years in America and “Where was your family 200 years ago?” at What’s Past is Prologue. Steve at Steve’s Genealogy Blog has also given the ‘Map Your DNA’ meme a try. I thought it was a fun idea, and had a number of potentially interesting applications, if I were a programmer and if I had any free time. Absent that, I thought I would at least try to replicate John’s idea by mapping my location in 2008 versus the locations of my Y-DNA and mtDNA in 1808, 200 years ago.

First, my Y-DNA. The blue dot on the following map of New York State is the location of my … Click to read more!

SeqWright Launches Personal Genomics Service

logo1.jpgAs I recently mentioned, SeqWright has launched a new Personal Genomics Service. Using a saliva sample, this service will analyze 930,000 SNPs from a customer’s genome using the Affymetrix 6.0 Human SNP Genotyping microarray. SeqWright will then report information back to the customer about “Genetic Health,” “Ancestral Origins,” and “Genealogy.” The cost of the service is $998. According to the website, they “will begin accepting orders for Genetic Profiling Services on Monday January 28 2008.” The official press release is available here.

From the consent form available on the SeqWright website:

“SeqWright will generate its client’s personal genomic data on the Affymetrix 6.0 Human SNP Genotyping microarray. This Array is capable of recognizing approximately 930,000 unique human SNP’s. However, due to individual sample and test variation the number of SNP genotypes that SeqWright will report for a given individual will be a fraction of those SNP’s.”

The SNPs that SeqWright will report are those that are believed to be associated with disease:

“SeqWright will only report SNP’s which we have deemed, through the analysis of publications with significant statistical size and power, to have an established association with a disease state or trait.”

SeqWright provides the usual and very necessary disclaimer that their information is NOT to be used as a substitute for … Click to read more!

1

The mitoWheel – Visualize the Mitochondrial Genome

A potentially very useful new tool for mitochondrial DNA sequences has just launched. The mitoWheel, announced today on Attila Csordás’ blog “Pimm – Partial immortalization” is a web-based graphical interface to visualize mtDNA. Attila is actually a member of the developing team for this project. According to the mitoWheel website:

“The mitoWheel is a graphical representation of the human mitochondrial genome. Use the left and right arrows to start browsing the sequence. You can also search for a nucleotide position, a gene, or a sequence motif by clicking in the search field, typing a term and pressing ENTER. Be sure to return soon for updates introducing further tools.”

According to Attila, “The sequence used is the standard Revised Cambridge Reference Sequence.” Here is a small screenshot of the tool:

Mitowheel1

As you can see, the CRS sequence is listed along the front of the interface, and is scrollable:

Mitowheel2

While I was exploring the new tool, I thought of a few (genetic genealogy-related) features that I would love to see:

    1. Ability to upload an entire sequence or list of mutations to be translated into your own personal graphical representation (with changes from the CRS highlighted, maybe even with annotated information about those mutations);
    2. Ability to compare to sequences side-by-side (your sequence v. the CRS, or your sequence v. your 4th cousins’, for example).

    This is a very interesting tool, and hopefully will be updated with new features, so stay … Click to read more!

3

Personal Genomics And the DNA Network

the_dna_network_logo The DNA Network was full of news about 23andMe, Knome, and the newly-announced 1000 Genomes Project, which plans to sequence (can you guess?) 1,000 genomes from around the world. The 1GP will “receive major support from the Wellcome Trust Sanger Institute in Hinxton, England, the Beijing Genomics Institute (BGI) Shenzhen, China and the National Human Genome Research Institute (NHGRI), part of the U.S. National Institutes of Health (NIH).” Source.

Here’s a brief roundup of all the latest regarding the 1GP:

New information about 23andMe, including the launch of their new blog, the spittoon:

Other stuff:

  • Scienceroll, “Knome Begins Sequencing First Clients.” Remember that Knome is currently charging customers $350,000 to have their entire genome privately sequenced. As I recently commented at Eye on DNA, I think the price tag is too high in light of recent developments in technology. This is actually amazing, considering that $350,000 would have been a bargain in January 2007. Companies hoping to make money from sequencing are going to learn to act quickly and adapt even faster.
  • SEQanswers.com, “deCODEme opens sample data set, check it out!

And last but not least, are you worried about hair loss? A new company called HairDX offers a test that will examine SNP(s) on the X-chromosome, but the … Click to read more!

6

And The Winner Of The FREE Genetic Genealogy Test Is…..

DNA HeritageJasia of Creative Gene! Jasia’s winning entry was from a post she wrote about the contest. If Jasia accepts the prize, she will discuss her testing experience or her results either on her blog or here at The Genetic Genealogist, which should be a lot of fun and will help genetic genealogy newbies gain some insight into testing. Congratulations Jasia!

If Jasia doesn’t claim the prize, or decides she doesn’t want it, the runner-up for this contest is Yann of Yann Klimentidis’ Weblog.

Thank you to everyone who wrote about the contest on their blog, subscribed to my feed, subscribed to my mailing list, or left a comment at the original post. Overall, 34 people entered the contest with a total of 117 entries! I met some new readers and read some fantastic posts about the blog. At the end of this … Click to read more!

8

The Latest 23andMe Update

23andme-logo1

Here are few of the latest sources of information or discussion about 23andMe:

Mark Fletcher at Wingedpig.com writes about some “23andMe Updates.” Fletcher notes that Andrew Scheidecker has written a program that will extract and download your own raw SNP data from 23andMe (http://www.scheidecker.net/personal-genome-explorer/). Scheidecker writes that the program doesn’t violate 23andMe’s terms of service, but I recommend confirming that for yourself before you use this program. Fletcher also links to Kevin Kelly at the Quantified Self, who writes “23andMe, Alzheimer’s disease, and ApoE.” Kelly notes (as has Fletcher) that the rs1702 and rs4420638 SNPs tested by 23andMe are resulting in “no call” for many individuals. These two SNPs are believed to be associated with Alzheimer’s disease.

HT & the Sheriff has decided to order a test at “Me, Me, Me (and 23).” Stay tuned for the results.

Jay … Click to read more!

The Genetic Genealogist’s Contest Reminder

This is just a last reminder that my contest to give away a free genetic genealogy test ends tonight at 11:59PM (EST). The contest rules are here. Don’t forget that you can enter multiples times by:

  1. Leaving a comment on the original contest post (here), or;
  2. Write a short review of the blog or the contest with a link to http://www.thegeneticgenealogist.com using the anchor text “genetic genealogy” and then leave a comment here with a link to the review, or;
  3. Subscribe to my feed and then email me (blaine_5 at hotmail.com) your name and the secret password found in the feed, or;
  4. Subscribe to my blog by email using the form in the far right sidebar.

I will announce the winner and the runner-up tomorrow, along with a list of every blog review or blogger that commented! I would like to thank everyone who has already written a review, subscribed to my blog, or left a comment. This contest has been a lot of fun, and I look forward to learning more about the winner’s experience with genetic genealogy. Good … Click to read more!