I’ve been meaning to write about recent two papers, one in Current Biology and one in Nature, that attempt to identify and characterize a relationship between genetic sequence or SNP and geography. Amazingly, both papers found a very strong correlation between genetics and geography.
From a news article regarding the paper in Nature (note that I haven’t verified that the paper supports the statement; HT: Yann Klimentidis’ Weblog):
"The map was so accurate that when Novembre’s team placed a geopolitical map over their genetic "map", half of the genomes landed within 310 kilometres of their country of origin, while 90% fell within 700 km."
Although there are some caveats, for example in one of the papers all of an individual’s grandparents had to have similar geographic origins in order for the method to identify ancestry, these types of studies will continue to discover and refine the methods and findings. As Kambiz stated at Anthropology.net, "With higher resolution GeneChips, ideally full genomes, and larger samples, we’ll be able see much more accurate genetic-geographic separations of populations."
On September 5th at the 2008 Federation of Genealogical Societies Conference in Philadelphia, Pennsylvania, I was interviewed by Dick Eastman.Â In the interview we discuss my blog, DNA testing in general, and my free ebook, “I Have the Results of My Genetic Genealogy Test, Now What?” (which is available for download in the sidebar of the blog).
“Houston is also home to Family Tree DNA, a company that offers the same services as Oxford Ancestors. Last year, Harvard professor Henry Louis Gates joined forces with Family Tree DNA to help African Americans looking for answers about their past. AfricanDNA, the company Gates launched in November 2007, offers both genetic testing and genealogical tracing services for African Americans.”
Welcome to the September 14, 2008 edition of Gene Genie!Â Bloggers have begun to pick up posting with the end of summer, and it seems like everyday there’s a bunch of new interesting posts about the human genome.
Yesterday I wrote about 23andMe’s decision to lower their price to $399 (down from $999) while adding more genealogically-relevant SNPs and partnering with Ancestry.com.Â Although I don’t have any further information about the new SNPs, I’ve seen a couple of interesting articles about the price drop around the blogosphere.
Aaron Rowe at Wired science writes “Human Genetics is Now a Viable Hobby.”Â He notes that the new price is “well within the reach of cash-strapped grad students, frugal genealogy buffs and other not-so-early adopters.”Â The comment thread is an interesting read as well.
23andMe just announced that the price of their service has dropped from $999 to $399.Â According to an article in the San Francisco Chronicle, the company lowered the price of testing to attract more customers and increase the size of their database.Â The article maintains that 23andMe will still bring in profit from the lower membership price, which is made possible by a “new, higher-density gene-scanning chip made by Illumina Inc. of San Diego.”Â From the press release:
“The new Beadchip, called the HumanHap550-Quad+, makes use of a four-sample format. 23andMe also has added improved custom content to the new Beadchip, which will include a broader range of Single Nucleotide Polymorphism (SNP) variations and rare mutations not found on the previous Beadchip, thereby providing more relevant data on published associations, as well as maternal and paternal ancestry.”
Knome, a personal genomics company that launched within the past year, has just delivered the first genomic sequencing to customers according to a report in the MIT Technology Review.
After paying $350,000 for sequencing, customers receive their genetic sequence on an 8-gigabyte USB drive in an engraved silver box.Â The USB is encrypted and contains special genome browsing software.
For the first time in history, it is unclear how many complete human genomes have been sequenced by scientists.Â Prior to Knome, we knew exactly how many had been completed.Â Now, and probably ever after, genomes will be sequenced and analyzed without all the typical fanfare and press releases.Â Instead of just 2 or 3 genomes, there will soon be tens of genomes, then hundreds, and then thousands.
Yesterday I posted the first part of a two-part interview with Colleen Fitpatrick, a forensic genealogist.Â In that interview, we discussed Colleen’s participation in a project to identify the remains located at a military crash site from 1948.
Today, we discuss her work on identifying the Titanic’s Unknown Child, among other projects.
The Genetic Genealogist:Â On April 17, 1912, two days after the RMS Titanic sank in the North Atlantic, the salvage vessel Mackay Bennett discovered the body of a young boy. The sailors paid for a monument, and the boy was buried in Fairview Lawn Cemetery in Halifax, Nova Scotia. In 2008, after an initial false identification based on dental records, the boy was identified as Sidney Leslie Goodwin. You were part of the team that identified Sidney. Can you tell us about that experience?
Colleen Fitzpatrick, Ph.D. is one of the most recognizable names in the field of forensic genealogy.Â She has authored two books entitled Forensic Genealogy and DNA & Genealogy, and continues to make headlines in this fascinating field.Â Here is just an excerpt from her biography, located at her website:
“Colleen Fitzpatrick, Ph.D., is the author of two of the best-selling books in genealogy.Â Forensic Genealogy has been widely recognized for its innovative forensic science approach to genealogical research.Â She has been featured on NPR’s Talk of the Nation radio program (July 2005), and has written cover articles for Internet Genealogy (June 2006), Family Tree Magazine (April 2006) and Family Chronicle (October 2005).Â Colleen writes a regular column for Ancestry magazine.”
This Friday, September 5th, I’ll be attending the FGS meeting in Philadelphia.Â I’m excited because this is my first big genealogy meeting (after 20 years of genealogy!), and because I get to sit and watch some great presenters discuss genetic genealogy.Â The program is here.
I hope to meet some other genealogy bloggers, if any of you are planning to attend!