Yesterday Science published a report from deCODE genetics in Iceland and a second report from academic colleagues in the United States and Canada that announced the discovery of a gene variant (a SNP) on chromosome 9p21 that results in an increased risk of heart attack (the abstracts are available online here and here). The SNP was discovered through genome-wide SNP analysis in Iceland and replicated in three groups of European descent in the United States. I don’t have access to either paper, but according to deCODE’s press release the variant is estimated to account for 20% of the incidence of heart attacks in Europeans, including one-third of early-onset cases (men and women age 50 to 60). Both companies used SNP Chips (that’s fun to say outloud), tiny gene chips … Click to read more!
Update: The podcast was updated to add the last 5 minutes of the interview (after the commercial break).Â As a result, the link to the podcast changed.Â I apologize to everyone who tried the old link – it should work fine now.
Market News First, a website dedicated to microcap markets, recently interviewed the CEO of DNAPrint Genomics, Inc.”Richard Gabriel, President and CEO of DNAPrint Genomics, Inc. spoke with MN1.com’s Rich Hancock on April 26th, 2007 about the Company’s innovative and cutting edge technology that aids law enforcement crime scene investigation (CSI) forensics, consumer applications in genealogy ancestry/genetic testing and its pharmaceutical and diagnostic applications. Mr. Gabriel highlights the Company’s recent advances in its pharmaceutical and diagnostic, and … Click to read more!
1. Who is GINA?
GINA isnâ€™t a â€˜whoâ€™, itâ€™s a â€˜whatâ€™. GINA stands for Genetic Information Non-Discrimination Act.
2. Okay, what is the Genetic Information Non-Discrimination Act?
GINA aims to protect individuals in a variety of different areas. The legislation would prohibit access to genetic information by insurance companies and would prohibit insurance companies from discriminating against an applicant based on genetic information, the refusal to submit genetic information, or for have been genetically tested in the past. Additionally, the Act would prohibit employers from using or collecting genetic information to make employment decisions. The Act also establishes a Genetic Nondiscrimination Study Commission that is charged with reviewing new developments in the … Click to read more!
This article is appearing in newspapers across the country (In the Rocky Mountain News [Thanks to Tim] and USA Today [Thanks to Megan]).Â Martin Marshall never believed that his father was actually his biological father, and testing has shown that he is not related to at least one of his brothers.Â Marshall then underwent Y-DNA testing in the hope of learning more about his father’s lineage.
“Marshall logged into an Internet database. He entered his DNA profile, and was astounded to find that virtually every person who closely resembled him genetically was named Sizemore.”
To date, Marshall does not know who his father was, but he is hoping that eventually the mystery will be … Click to read more!
In 2005 the Wellcome Trust established a Â£2.3 million project (roughly 4.5 million USD) at the University Oxford to examine the genetic makeup of the United Kingdom. The project would be led by the renowned geneticist and Oxford Professor Sir Walter Bodmer, joined by Oxford Professor Peter Donnelly (a population genetics and statistics expert) and the Wellcome Trust Principal Research Fellow Professor Lon Cardon.
The goal of the project is to establish a knowledge base for analyzing genes that are linked to disease. To do this, the researchers hoped to gather DNA from 3000 to 3500 volunteers throughout the UK who live in the same area as their parents and grandparents. Each volunteerâ€™s DNA will be tested for 2000 SNPs (single … Click to read more!
The Guardian, a newspaper based in England, recently published an article about genetic genealogy entitled â€œThe appliance of science.” Itâ€™s an interesting article that looks at the pros and cons of genetic testing for genealogical purposes.
The journalist quotes Chris Pomery, author of the up-coming book â€œFamily History in the Genes: Trace Your DNA and Grow Your Family Tree.â€
“In specific cases, genetics is a very useful tool, but it is not a panacea,” he says. “We’re not even close to the situation where, if you’re starting to research your family history, you should begin with a DNA test. At Â£100 or so a throw it’s a lot of money, and you can progress your research a long way first for free.”
I agree completely. Genetic genealogy is most useful for researchers that are attempting to verify a … Click to read more!
Although the article in today’s New York Times – “DNA Tests Offer Immigrants Hope or Despair” by Rachel L. Swarns – uses traditional paternity or maternity tests and not genetic genealogy tests, the emotional results of the tested can often be the same. What if DNA proves that your father isn’t your biological father? What happens when there is uncontestable proof that there was an NPE (non-paternal event) in your great-grandfather’s ancestry?
According to the article, federal officials in the Immigration Department are using “genetic testing to verify the biological bonds between new citizens and the overseas relatives they hope to bring here, particularly those from war-torn or developing countries where identity documents can be scarce or doctored.”
For example, Isaac has … Click to read more!
Here are some recent news articles that mention the use of genetics in traditional … Click to read more!