The Genetic Genealogist

Over at The Legal Genealogist (one of my favorite new blogs!), blogger Judy Russell, J.D., CG discusses Ancestry.com’s new autosomal DNA testing service in “Science and the “10th” cousin.”

As I noted in a recent blog post (see “WDYTYA Reveals More Information About Ancestry.com’s New Autosomal DNA Testing“), autosomal DNA testing was featured in the recent episode of Who Do You Think You Are with actor Blair Underwood.  After revealing Mr. Underwood’s biogeographical estimates (74% African American and 26% European), they revealed a genetic cousin found in the Ancestry.com’s database:

The service identified a distant cousin (somewhere around the 10^th cousin range) who lived in Cameroon (an Eric Sonjowoh). Mr. Sonjowoh was already in the Ancestry.com database, which is why they were able to compare him to Mr. Underwood. According to Eric, someone approached him in 2005 and asked him for his DNA because African Americans were trying to trace their family back to Cameroon. I’m not sure what database the DNA was in, but it shows that Ancestry.com has pre-populated its database with at least some samples from other public and/or proprietary data sources.

Ms. Russell expresses concerns over the identification of the relationship between Mr. Underwood and Mr. Sonjowoh as “1oth Cousins:”

I have a bit of an issue with telling person A (Blair Underwood) that person B (Eric Sonjowoh) is a 10th cousin when there isn’t a prayer of a paper trail to support that statement — and the science isn’t good enough to say it either.

She notes – very correctly – that autosomal testing alone cannot identify a relationship as being 10th cousins rather than anything ranging from 5th, 12th, or 15th cousins, or even beyond.

As you can see from my summary above, I had assumed that the label “10th Cousins” was not intended to be an exact identification of the relationship (I wrote: “somewhere around the 10th cousin range”), but an approximation similar to those used by both 23andMe (for example, “3rd to Distant Cousin”) and Family Tree DNA (for example, “5th Cousin – Remote Cousin”).  Unfortunately, it’s difficult to determine from the portion of the user interface we saw in the program whether or not the “10th cousins” applies to a range or is intended to be a more definitive determination.

In any event, I agree with Ms. Russell’s conclusion.  It is vital that users of any autosomal DNA testing service understand both the capabilities and limitations of the science, and that testing providers work to educate their customers.  It will be interesting to see more of the Ancestry.com user interface when the product officially launches.

Here’s a few links to some other discussion of DNA testing and Ancestry.com’s service following Mr. Underwood’s episode of WDYTYA:

• “Blair Underwood, Who Do You Think You Are?” at tracingthetree;
• “Blair Underwood talks tracing his African roots and ‘Streetcar’ role” at the grio; and
• “Blair Underwood’s African Roots on WDYTYA?” at Ancestor Search Blog.

By the way, a congratulations to Ms. Russell on her recent certification as a Certified Genealogist!

[Update (2/24/12): Some genealogy forums are reporting that callers to Ancestry.com are being told that the autosomal DNA test will publicly launch in approximately 1 month (late March or early April).]

Tonight’s episode of Who Do You Think You Are? featured African-American actor Blair Underwood. For those not familiar with Who Do You Think You Are, the 1-hour program examines the genealogy of a celebrity, typically focusing on one or two of their most interesting families.

DNA Testing

This episode was of particular interest to me because it featured Ancestry.com’s new autosomal DNA testing service, which I’ve written about before (see “Ancestry.com’s Autosomal DNA Product – An Update”). While there wasn’t too much new information about the DNA product in this episode, it was an interesting sneak peek at the service.

In the beginning of the episode, as Mr. Underwood visits with his family to get a start with his genealogy, he shows a DNA collection kit with two long swabs and a mail return envelope. Ancestry.com is using cheek swabs rather than a saliva sample to collect DNA.

Admixture Results

Later in the episode, Mr. Underwood reviews his DNA test results with Dr. Ken Chahine (LinkedIn profile), who is described as the “General Manager Ancestry DNA” in the episode. Dr. Chahine has a Ph.D. in biochemistry and a J.D. (very similar to my own background). According to Dr. Chahine, the test Mr. Underwood used examined approximately 700,000 “links” (or SNPs) in the DNA chain.

Mr. Underwood’s results suggested that the DNA examined was approximately 26% European and 74% African, which is a fairly common admixture for African Americans. Under the “European” tab of the user interface, he was described as 20% French/Swiss and 6% German. Under the “African” tab, the results showed 27% Bamoun, 22% Brong, 13% Yoruba, and 12% Igbo (a total of 74%).

Genetic Cousins

Next, Dr. Chahine asked, “Where would we find your closest DNA matches?” In other words, the Ancestry.com autosomal testing service will also include the ability to identify genetic cousins in the database.

The service identified a distant cousin (somewhere around the 10^th cousin range) who lived in Cameroon (an Eric Sonjowoh). Mr. Sonjowoh was already in the Ancestry.com database, which is why they were able to compare him to Mr. Underwood. According to Eric, someone approached him in 2005 and asked him for his DNA because African Americans were trying to trace their family back to Cameroon. I’m not sure what database the DNA was in, but it shows that Ancestry.com has pre-populated its database with at least some samples from other public and/or proprietary data sources.

Interestingly, Dr. Chahine indicated that Mr. Underwood and Mr. Sonjowoh are related through Mr. Underwood’s paternal line. I’m guessing that they determined this by also testing one of Mr. Underwood’s parents (either directly testing his father, or by process of elimination by testing his mother).

At the end of the episode, Mr. Underwood and his father traveled to Cameroon to meet Mr. Sonjowoh and his family, which was a touching reunion. Although their relationship is extremely distant (perhaps as much as 300 to 400 years), it provided Mr. Underwood with a connection to his roots in Africa.

As I’ve stated many, many times in the past, the future of genetic genealogy is combining test results with both family trees and paper records.

Today, MyHeritage and Family Tree DNA announced a partnership that will bring that future one step closer to reality.  MyHeritage will offer a full line of tests (13 in total) through FTDNA, including these basic introductory tests (with discounts – not shown below – for MyHeritage subscribers):

• Y-DNA12 (12 Y-STR markers) – $99
• mtDNA (HVR1 region) – $99
• Family Finder (autosomal test) – $298

The FAQ page for the tests is here (and I note that although they currently do not allow import of test results from other providers, they plan to in the future).  I wonder if existing FTDNA test-takers can import their results?

Given MyHeritage’s worldwide reach and enormous membership (62 million members around the world!), it will be interesting to see whether this new partnership expands genetic genealogy testing in other parts of the world, which have been slow to try this technology.

Today’s Press Release:

MyHeritage brings DNA testing to the global community

World’s largest family network offers DNA testing to a new global audience – enabling millions of families to discover their ethnic roots and previously unknown relatives

PROVO, Utah & LONDON & TEL AVIV, Israel – February 16, 2012: MyHeritage, the most popular family network on the web, announced today the integration of DNA testing into its core family history offering. The move adds genetic genealogy to the company’s suite of tools for researching family history, used by millions of families around the world.

With more than 62 million registered users and 21 million family trees, MyHeritage has become the trusted home on the web for families wishing to explore their family history, share memories and stay connected. With the new biological layer added to the MyHeritage experience, users can now enjoy a service combining science, intuitive web features and social networking for discovering and sharing their family legacy.

“DNA testing provides a fascinating new way to discover one’s origins and find previously unknown relatives”, said MyHeritage Founder and CEO Gilad Japhet. “Offering the highest quality DNA tests to our tens of millions of users around the world in 38 languages, and providing DNA matches with hundreds of thousands of people who have already had their DNA tested, significantly advances our mission of bringing family history to the masses. By combining DNA with our innovative Smart Matching™ technology, families will be closer than ever before to constructing a more complete picture of their history”.

DNA is the hereditary material in humans and almost all other organisms. By purchasing a simple cheek-swab DNA test, users can now use information contained in their DNA to find present-day relatives who share a common ancestor up to many hundreds of years ago. A DNA test can also reveal ethnic origins such as Native American, African or Jewish descent on paternal or maternal lines, as well as uncover ancestral information for those who were adopted.  While DNA tests can break through brick walls in family history research by revealing biological relations, MyHeritage’s flagship Smart Matching™ technology then steps in to help piece together the paper trail by uncovering how the family trees of related people actually connect. In addition, people with the same paternal surname can get together via MyHeritage to see if they’re related by DNA.

MyHeritage is introducing today a wide range of DNA tests to meet different research objectives and budgets, with special discounted prices for MyHeritage subscribers starting from as low as $84. Users can identify the deep ancestral origins of their direct paternal line (Y-DNA), of their direct maternal line (mtDNA), find relatives across all lines via autosomal DNA (Family Finder), receive a percentage breakdown of their ethnic roots and confirm or disprove whether someone is a close relative. View the full list of the DNA kits on MyHeritage and a list of Frequently Asked Questions about DNA tests on MyHeritage.

For the analysis of users’ DNA tests and the DNA matching, MyHeritage is working with long-time partner and global leader in genealogy DNA, Family Tree DNA. Pioneers of genetic genealogy and with a state-of-the-art laboratory, Family Tree DNA has established the world’s largest DNA database for genealogy and is well known for its work with National Geographic on the Genographic Project. All information is kept strictly confidential and is never shared.

Bennett Greenspan, President and CEO of Family Tree DNA said “We’re proud to work with MyHeritage to bring DNA testing to a much wider, global audience. The phenomenal size and reach of the global MyHeritage family network will create new horizons in collecting DNA data, helping many more people discover their ancestral origins”.

About MyHeritage

MyHeritage is the most popular family network on the web. Millions of families around the world enjoy having a private and free place for their families to keep in touch and to showcase their roots. MyHeritage’s Smart Matching™ technology empowers users with an exciting and innovative way to find relatives and explore their family history. Following the November 2011 acquisition of FamilyLink in Provo, Utah, MyHeritage offers billions of historical records through its website WorldVitalRecords.com. With all family information stored in a secure site, MyHeritage is the ideal place to share family photos and preserve special family memories. The site is available in 38 languages. So far more than 62 million people have signed up to MyHeritage. The company is backed by Accel Partners and Index Ventures, the investors of Facebook and Skype. For more information visit www.myheritage.com

Press Contact

Daniel Horowitz                                   Schelly Talalay Dardashti                   Mark Olsen

Chief Genealogist                               US Genealogy Advisor                       Affiliate Manager

MyHeritage.com                                 MyHeritage.com                                 MyHeritage.com

Daniel@MyHeritage.com                   (505) 994.1554                                    (801) 687.0599

As you may have heard, I recently made my 23andMe and Family Tree DNA autosomal testing results available for download online at “mygenotype,” and dedicated the information to the public domain (if dedicating DNA sequence to the public domain is even possible – I’m currently doing some research in this area and expect to write more in the future).

At “mygenotype” you can download the following:

My Family Tree DNA Results:

1. Affymetrix Autosomal DNA Results (2010)
2. Affymetrix X-Chromosome DNA Results (2010)
3. Illumina Autosomal DNA Results (2011)
4. Illumina X-Chromosome DNA Results (2011)

My 23andMe Results:

1. V2 Results (2008)
2. V3 Results (2010)
3. Y-DNA Results (2010)
4. mtDNA Results (2010)

You can also find my SNPedia Promethease reports:

• Promethease Report using an early version of Affymetrix Family Finder DNA Results

• Promethease Report using V2 23andMe DNA Results

• Promethease Report using pooled 23andMe and Family Finder DNA Results

In addition to my genome, Razib Khan of Gene Expression has a spreadsheet of approximately 48 other genomes that are available for download online.

A Challenge To YOU

Now that the information is out there, available to anyone who might be interested, it remains to be seen who might be interested in the information.

Indeed, as evidenced by Razib’s spreadsheet, while dedicating a genome to the public domain has only been done by a small handful of people worldwide, it isn’t as novel as it was just a few months ago.

So, I’m challenging everyone who reads this to download my data and analyze it to find the most interesting or surprising results.  For example, you could use my most recent 23andMe V3 data.

I’ve already done a fair amount of analysis myself, including the Promethease reports above (and see here), and a recent blog post about my vastly increased Type 2 Diabetes risk.  However, perhaps there’s a recent but relatively study that applies, or perhaps there’s a story you can weave with a handful of SNPs. Or, even better, what can you tell me about my ancestry other than mtDNA and Y-DNA haplogroups? Don’t worry about the strength of the study, reproducibility, etc. – I’m aware of the uncertainties associated with this type of research, and my goal here is to make people aware of possibilities.

Please post your findings in the comments below, and in two weeks I’ll pick the most surprising or interesting findings and make them the focus of a new blog post.

Can you surprise me with my own genome?

Daniel Vorhaus of the Genomics Law Report is also a member of the steering committee of the GET (“Genomes, Environments, Traits) Conference 2010. This unique conference, to be held on Tuesday, April 27, 2010 will gather together some of the biggest names in personal genomics, as well as most of the limited number of the people who have released their entire genomes to the public. Tickets for the conference go on sale today here.

As part of the GET Conference 2010, the new BioWeatherMap initiative will officially launch. According to the project’s website, BioWeatherMap is “a global, grassroots, distributed environmental sensing effort aimed at answering some very basic questions about the geographic and temporal distribution patterns of microbial life. Utilizing the power of high-throughput, low cost DNA sequencing and harnessing the drive of an enlightened public we propose a new collaborative research approach aimed at generating a steady stream of environmental samples from many geographic locations to produce high quality data for ongoing discovery and surveillance.”

Unfortunately I will be unable to attend the GET Conference 2010, although I’m sure I and anyone else interested in the Conference will all be able to participate in at least a limited manner through social media.

The Press Release

Personal Genome Pioneers to Convene at the Inaugural Genomes Environments Traits (GET) Conference: Luminaries at landmark gathering to shed light on diverse impact large-scale personal genome sequencing will have on everyday life

BOSTON, Mass. (February 18, 2010) — Worldwide fewer than 20 individuals have had their genomes sequenced and made publicly available, and on Tuesday, April 27, for the first time, nearly all of them will appear together, along with a select group of business leaders and scientific visionaries, to share their experiences and to provide a look ahead at how personal genomics will rapidly and broadly impact society. This historic gathering will take place at the inaugural Genomes Environments Traits (GET) Conference as part of a day-long thought leadership forum, exploring the myriad ways in which the integration of personalized genomic, environmental and trait information will shape the ways in which we access and interact with our genetic information.

“The GET Conference 2010 marks the last opportunity in history to gather a majority of individuals in the world with public personal genome sequences in a single venue,” says George Church, founder and principal investigator of the Personal Genome Project and professor of genetics at Harvard Medical School. “With rapid advances in technology, the number of individuals with personal genome sequences is expected to rise dramatically, from dozens today to thousands by 2011 and a million or more individuals within the next few years.”

The morning portion of GET Conference 2010 will feature wide-ranging discussions during which personal genome pioneers and globally recognized leaders of genomic science and industry, including Misha Angrist, George Church, Jay Flatley, Henry Louis Gates, Jr., Rosalynn Gill, Seong-Jin Kim, Greg Lucier, James Lupski, Stephen Quake, Dan Stoicescu and James Watson, will share their experiences and discuss the future of personal genomics. Award-winning science journalists Carl Zimmer and Robert Krulwich will moderate the discussions.

These experts will re-convene in the afternoon for a series of breakout sessions with other thought leaders and conference participants in a series of intimate discussions focused on the role personal genomes play in understanding ancestry, family life, nutrition, and disease risk, as well as the marketplace for products and services that utilize the analysis of genomic and environmental information, including new drug therapies, consumer products and law enforcement applications.

The afternoon program will additionally showcase:

• Four “prototypes of the future” sessions highlighting the next generation of personalized genomic products, services and activities and moderated by the executive editor of WIRED and author, Thomas Goetz.

• The public debut of the BioWeatherMap initiative, a collaboration between scientists and the public using next-generation sequencing platforms to address the fundamental question: “How diverse is the microbial life around us and how can we use that information to our advantage?”

The GET Conference 2010 will take place on Tuesday, April 27, 2010 from 8:00 a.m. – 8:00 p.m. at the Microsoft New England Research and Development Center in Cambridge, Mass. The event will be limited to 200 registrants. To register for the GET Conference 2010, visit http://www.getconference.eventbrite.com/.

About the GET Conference 2010

The first annual GET Conference will gather 200 scientific, industry and thought leaders in the fields of personal genomics, personalized medicine, microbiomics and systems biology, as well as prominent hedge fund managers, VCs, private investors, and philanthropists, in an intimate venue to consider the present and future of personal genomics.

All proceeds from the GET Conference will benefit PersonalGenomes.org, a 501(c)(3) charitable organization which supports the Personal Genome Project and whose mission is to serve as a global ambassador for emerging technologies and knowledge that will positively impact the health and well-being of humankind. For more information, visit www.getconference.org, or e-mail info@getconference.org.

Conference sponsors include: Alan & Priscilla Oppenheimer Foundation; Knome; Life Technologies; Microsoft; OHO Interactive; Procter & Gamble; Robinson, Bradshaw, & Hinson; Schwartz Communications; and Third Rock Ventures. Limited sponsorship opportunities are still available. For more information email: info@getconference.org.

About the Personal Genome Project

The Personal Genome Project is an open-ended research study that aims to improve the understanding of genetic and environmental contributions to human traits. The project is currently enrolling members of the public who are willing to share their genome sequence and other personal information with the scientific community and the general public. For more information, visit http://www.personalgenomes.org/.

• DNA Test Index has a great index of DNA testing providers, including genetic genealogy testing companies.  Via @genomicslawyer – an atypically complete list of genetic test providers: http://bit.ly/2f8FLW.

• ISOGG, the International Society of Genetic Genealogy, has a new information page at “I’ve Tested at 23andMe, Now What?“  The site includes a variety of tools to help you further explore your ancestry, including EURO-DNA-CALC and Promethease, among others.

• Family Tree DNA has a new Holiday Sale, as summarized at the U4 Haplogroup website.  The FTDNA ordering page also has the holiday prices.

• Linda Avey, co-founder of 23andMe, has started a new blog entitled The Life & Times of Lilly Mendel.  I’m looking forward to some interesting reading as Linda establishes the Brainstorm Research Foundation dedicated to the study of Alzheimer’s disease.

• The Genomics Law Report continues the fascinating What ELSI is New? series, including a contribution from yours truly.

ISOGG, the International Society of Genetic Genealogy, has a “Success Stories” page where it posts short summaries of just a few the many successes that genetic genealogy has helped people achieve.  Today I noticed that there are several new summaries regarding “Autosomal DNA Successes,” both of which were the result of 23andMe’s new Relative Finder (currently still in beta testing).

Relative Finder

As I recently wrote, Relative Finder is a feature at 23andMe that allows users to compare their autosomal DNA to the autosomal DNA of others to potentially find cousins.  This has long been done with Y-DNA and mtDNA, but this is one of the first times this has been done with autosomal DNA.

Success Story #1

The first success story is from someone who used Relative Finder to identify a huge number of potential cousins.  After connecting one of his or her potential 4th cousins, the individuals discovered that they have similar surnames from a certain location in common (in addition to DNA on chromosomes 3 and 10).  This individual also wisely noted that s/he now has “a good idea of the path that two of my DNA segments took through my pedigree to get to me.”  This is something I wrote about recently in “The Future of Genetic Genealogy – Tracing DNA To Individual Ancestors.”

Success Story #2 – A First?

The second success story is about two Relative Finder users who worked together to identify a line that they had in common, potentially identifying segments of DNA passed to them from a couple who were born in the 1730’s.  This is a very interesting result, and I wonder if it is the first time that genealogists have identified a segment of DNA that they inherited from distant autosomal ancestors (i.e. not their Y-DNA or mtDNA lines) outside of the medical realm.

Conclusion

I know I’ve mentioned this a great deal lately, but I again emphasize that geneticists and genealogists will be seeing much more of this type of success story in the future.

In January I wrote about Benjaman Kyle, an amnesiac who was found on August 31, 2004 next to a dumpster behind a Burger King in Richmond Hill, Georgia.  In that post, “Using Genetic Genealogy to Solve the Mystery of Benjaman Kyle,” I suggested that a Y-DNA test might be helpful in elucidating Mr. Kyle’s biological surname.  Y-DNA testing has shown to be highly useful for identifying unknown surnames (see here and here), and so I contacted Mr. Kyle to suggest the possibility.

The Results Are In

Shortly thereafter, Mr. Kyle took a 67-marker test from Family Tree DNA.  The results, announced it seems by Kimberly Powell of Kimberly’s Genealogy Blog, suggest that his surname might actually be POWELL or a variant thereof.  His results are now part of the Powell Surname DNA Project as kit #140314 where he very closely matches the “Joseph Powell Group.”  See more here.  From Kimberly’s post:

A 50/60 year old amnesia victim going by the name of Benjaman Kyle recently had his Y-DNA tested in an attempt to learn something about his origins; resulting in a close 37 marker connection with several members of the POWELL Surname DNA surname project at FamilyTreeDNA. Interestingly, just like the Unclaimed Persons Web site, founded by Megan Smolenyak, which brings together genealogists with medical examiners, coroners, and investigators searching for next of kin of recently deceased individuals, amnesia victims also have groups of volunteers who help try to reunite them with family. You can read more of the discussion on Benjaman Kyle at WebSleuths.com, which is where using genealogy as a possible tool was suggested.

The Indianapolis Star ran a story last month – Man with Amnesia Still Searching for his Past – that mentioned the DNA testing but failed to mention the potential POWELL link.

Proof?

This isn’t proof that Benjaman’s last name before he suffered from amnesia was Powell.  He might have legally changed his name, or there might have been some other non-paternal event that introduced the Y-DNA into the family (infidelity, adoption, etc…) such that Benjaman possessed the [potentially] Powell Y-DNA at birth but did not have the Powell surname.  In any event, this is a new clue that might help Mr. Kyle rediscover his identity.

I’ve been working on a presentation regarding the future of genetic genealogy, and one aspect of that future is the ability to trace DNA (SNPs, mutations, haplogroups, etc…) through recent history as the result of combining extensive genomic sequencing with massive family tree information.  Although the ability to do this will have many uses (both for genealogy and for personalized medicine), it will also raise a number of privacy issues, as a recent paper suggests.

A New Privacy Study

In “Inferential Genotyping of Y Chromosomes in Latter-Day Saints Founders and Comparison to Utah Samples in the HapMap Project,” author Jane Gitschier uses a combination of FamilySearch (http://www.familysearch.org) and Sorenson Molecular Genealogy Foundation (http://www.smgf.org/) to elucidate the Y-chromosome signature of two founders of the LDS Church.  Gitschier then used that information to determine whether anyone who contributed DNA to the HapMap project was related to these individuals via the Y-chromosome (none appeared to be).  However, Gitschier was able to predict the surname of many of the HapMap participants using these databases.

This research is related to two posts I wrote last October about using genetic genealogy results to determine surnames (“DNA Could Reveal Your Surname, Of Course,” and “More On Revealing Surnames Using Genetic Genealogy”).  I first mentioned this research last September when I highlighted some of the most interesting abstracts submitted for the American Society of Human Genetics’ November meeting (see here).

The Abstract:

“One concern in human genetics research is maintaining the privacy of study participants. The growth in genealogical registries may contribute to loss of privacy, given that genotypic information is accessible online to facilitate discovery of genetic relationships. Through iterative use of two such web archives, FamilySearch and Sorenson Molecular Genealogy Foundation, I was able to discern the likely haplotypes for the Y chromosomes of two men, Joseph Smith and Brigham Young, who were instrumental in the founding of the Latter-Day Saints Church. I then determined whether any of the Utahns who contributed to the HapMap project (the “CEU” set) is related to either man, on the basis of haplotype analysis of the Y chromosome. Although none of the CEU contributors appear to be a male-line relative, I discovered that predictions could be made for the surnames of the CEU participants by a similar process. For 20 of the 30 unrelated CEU samples, at least one exact match was revealed, and for 17 of these, a potential ancestor from Utah or a neighboring state could be identified. For the remaining ten samples, a match was nearly perfect, typically deviating by only one marker repeat unit. The same query performed in two other large databases revealed fewer individual matches and helped to clarify which surname predictions are more likely to be correct. Because large data sets of genotypes from both consenting research subjects and individuals pursuing genetic genealogy will be accessible online, this type of triangulation between databases may compromise the privacy of research subjects.”

In November 2007 I estimated that as of that date 600,000 to 700,000 DNA testing kits had been sold by genetic genealogy companies and that the number was increasing by 80,000 to 100,000 kits per year  (see “How Big is the Genetic Genealogy Market?”).  I ended that article with a prediction:  “As the interest in genetic genealogy grows, I predict that the 1 millionth genetic genealogy customer will push the ‘buy’ button as early as 2009.”

It seems my prediction might not have been too far off.  This week, Family Tree DNA issued a press release stating that the company had recently received an order for the 500,000th testing kit.

FTDNA’s Press Release:

HOUSTON, February 9, 2009 (For Immediate Release) – Family Tree DNA (http://www.familytreedna.com), the world leader in genetic genealogy, announced today that it received its 500,000^th DNA test order for genealogy and anthropology purposes.

This number of historic significance includes Family Tree DNA’s own customers as well as the public participation samples in National Geographic and IBM‘s Genographic Project (www.nationalgeographic.com/genographic), which are also processed by Family Tree DNA.

Founded in April 2000, Family Tree DNA was the first company to develop the commercial application of DNA testing for genealogical purposes that had previously been available only for academic and scientific research. Almost a decade later, the Houston-based company continues to establish standards and create new milestones in the increasingly popular and rapidly growing field of genetic genealogy, whereas other companies have came to the market space looking for the business opportunity, but offering tests of lesser value.

Presenting the most popular and wide-ranging DNA-testing service in the field of genetic genealogy, Family Tree DNA prides itself on its commitment to the practice of solid, ethical science. Family Tree DNA is the only company that provides all customers with a guaranteed assignment of ancestral origins and places their records in our secured database – the largest in the world for matching purposes, which in turn means increased chances of finding long lost relatives. In that regard, Family Tree DNA is an important resource for the three million people in the United States who either were adopted or descend from adoptees.

Since its inception, Family Tree DNA has been associated with the Genomics Analysis and Technology Core at the University of Arizona as well as some of the world’s leading authorities in the fields of Genetics and Anthropology. In 2006 Family Tree DNA established the state-of-the-art Genomics Research Center at its headquarters in Houston, Texas, where it currently performs R&D and processes over 200 types of advanced DNA tests for its customers.

Family Tree DNA currently has representative offices in Europe and the Middle East.