Another great article from the Genomics Law Report (if you arenâ€™t already reading this new blog, you should be) – â€œIs the ACCPâ€™s Call for Greater Governmental Regulation of DTC Genetics Premature?â€
Barbara Ameer and Norberto Krivoy of the American College of Clinical Pharmacology (ACCP) have an article (pdf) in The Journal of Clinical Pharmacology that promotes regulation of DTC genetic tests (which could conceivably include genetic genealogy tests).Â The Genomics Law Report analyzes the paperâ€™s arguments and concludes with the following:
â€œWithout convincing evidence of the harms of DTC genetic testing, it remains difficult to fully justify more rigorous governmental regulation, or to anticipate its content, structure or ultimate effect, which perhaps explains why such regulation continues to remain just over the horizon.â€
If youâ€™re interested in this area, click over to the Genomics Law Report and read this article (as well as the original ACCP … Click to read more!
[PLEASE NOTE:Â The Onion is a satirical site meant for ENTERTAINMENT and social commentary purposes only.Â The following study is NOT real!]
The Onion, an infamous mock news site has a (surprisingly intelligent) article today entitled “7 Million People Direct Descendants Of Single Smooth-Talking Ancestor” about a “study” that has found that millions of people around the world have a genetic marker that links them to “a single smooth-talking common ancestor.”
Randy Seaver of Genea-Musings brings the article to my attention (thank you Randy!):
The headline screams “7 Million People Direct Descendants of Smooth-Talking Ancestor” — see the article here in the Science and Technology section of The Onion. It sounds right up the genetic genealogy alley, doesn’t it? Megan, Blaine, Emily – why haven’t you written about this guy? Are 7 million descendants not enough?
Gwilym of Many Conquests
According to the article, after analyzing 4,000 samples from around the world, the Baltimore, Md. researchers announce that “the lineage appears to have originated with a highly virile ninth-century Welsh nobleman known as Gwilym of Many Conquests”:
“This is one of the largest diasporas known to have descended from a single progenitor,” said head researcher Lawrence Ghilcrest, adding that DNA evidence now corroborates stories about the Welshman that historians once dismissed as myth. “To have propagated his genetic material so effectively, and across so much territory, we can only infer Gwilym was quite the charmer.”
The article is clearly a reflection of several recent studies suggesting a link between prevalent traits or genetic markers and an ancient “prolific” … Click to read more!
A new blog called the Genomics Law Report went live today, promising to provide “news and analysis from the intersection of genomics, personalized medicine and the law.”Â This blog will undoubtedly be a must for anyone interested in personal genetics.Â Daniel MacArthur at Genetic Future has already provided a brief summary.
From the introductory … Click to read more!
An article appears in today’s Asheville Citizen-Times (here) about genetic genealogy. Although brief, the article summarizes the sciences behind Y-DNA and mtDNA testing, and focuses on the use of genetic genealogy to explore the “Clark” surname.
With the famous Thomas Jefferson-Sally Hemmings case, folks began to realize that DNA testing techniques could give answers and break down brick walls as never before.Â While DNA will never replace standard research and primary documentation, it can be considered a tool to be used hand in hand with standard research.
via citizen-times.com and familybuilder
Posted via web from … Click to read more!
Five bioethicists have published a paper in today’s issue of Science – The Illusive Gold Standard in Genetic Ancestry Testing (paid subscription required) – calling for government regulation of genetic ancestry testing (aka genetic genealogy). There is an accompanying press release: Stanford Bioethicist and Colleagues Call for Federal Regulation of Genetic Ancestry Testing (another press release is available here).
I highly respect the work of these authors, and I appreciate their efforts to educate the public about these issues. I do, however, wonder why the article was published in Science. The article mostly rehashes arguments found in a number of other articles (including from a very similar 2007 Science article (link) with some of the same authors) without adding any new research or supporting evidence. This is my greatest criticism of this and related articles – much of the … Click to read more!
Journalists Peter Aldhous and Michael Reilly write about using DNA obtained from a drinking glass and other sources to â€œhackâ€ someoneâ€™s genome.
In â€œSpecial investigation: How my genome was hacked,â€ the authors use a variety of consumer-available DNA services to prepare and amplify genomic DNA in order to send it away for analysis by deCODEme.Â They used deCODEme, it appears, because 23andMe and Navigenics use saliva collection, and â€œit would be hard to convert [the] amplified DNA sample into a form that closely mimicked saliva.â€Â They did use 23andMe, however, as a control.Â Interestingly, the cost of the entire process was about $1,700 for lab services (preparation and amplification) and $985 for deCODEmeâ€™s service.
From the … Click to read more!
Although I can hardly hope to introduce or discuss these recent events any better than Daniel MacArthur has already given at Genetic Future, I will at least bring this new information to your attention.
Last Wednesday the New York Times printed â€œMy Genome, My Selfâ€, an article written by Stephen Pinker, one of the Personal Genome Projectâ€™s â€œFirst 10.â€Â In the article, Pinker talks about his experience with genome sequencing through the PGP.Â It is especially interesting since Pinker analyzes the issue from the point of view of a psychologist.Â I highly recommend reading this article if you are at all interested in personalized medicine or genetics.
Much of the article discusses the confusing results that are returned by genome/disease analysis, due to … Click to read more!
An international team of researchers have concluded that humans entered the Americas from Asia along at least two different paths.Â By studying two rare mtDNA haplogroups found in Native Americans â€“ D4h3 and X2a â€“ the researchers conclude that D4h3 spread into the Americans along the Pacific coast while X2a entered through the ice-free corridor between the Laurentide and Cordilleran ice sheets.
From the Press Release:Â â€œSix major genetic lineages account for 95 percent of Native American mtDNA and are distributed everywhere in the Americas,â€ said first author Ugo Perego, director of operations at SMGF. â€œSo we chose to analyze two rare genetic groups and eliminate that â€˜statistical background noise.â€™ In this way, we found patterns … Click to read more!
Image via Wikipedia
I’m currently in the middle of third-year law school exams, so I thought I’d do a round-up of all the interesting stories I’ve seen over the past week or two.
Holiday Specials on DNA Testing
First, it appears that most of the major genetic genealogy companies are offering special deals for the holidays:
Family Tree DNA announces a holiday sale – FTDNA is offering reducing pricing for customers who are part of or join a DNA project. For example, a 37-marker Y-DNA test is reduced to $119, down from $149.
Ancestry.com announces holiday sale – buy a DNA test between now and December 31st, and you’ll receive 40% off. For example, a 33-marker Y-DNA test is $89.40 (usually $149) and their mtDNA test is $107.40 (usually $179).
African Ancestry announces a holiday sale – their MatriClan and PatriClan tests, which are normally $349, are on sale for $275.
Genetree offers a special first birthday sale – I’m not sure if this sale is open to everyone … Click to read more!
A new article in Ancestry Magazine, “Meeting My New Family,” details a recent meeting of genetic relatives in Chicago.Â The author is Howard Wolinsky, who has written other articles in the field of genetic genealogy (see, for example, an article in EMBO about 2 years ago).Â As Howard describes, the meeting wasn’t a traditional family reunion:
“We are a new kind of cousin. Until a few days ago, we were strangers who just happened to have had our DNA analyzed. Then we discovered we matched one another to varying degrees. Most of us have common Jewish connections. And we learned that we come from relatively rare branches of the human DNA tree. Our mothersâ€™ mothers came from the HV branch. Our fathersâ€™ fathers came from the G group.”
The full text of the article is … Click to read more!