Comments on: Are Disease-Causing mtDNA Mutations Common? http://www.thegeneticgenealogist.com/2008/08/05/are-pathogenic-mtdna-mutations-common/?utm_source=rss&utm_medium=rss&utm_campaign=are-pathogenic-mtdna-mutations-common Adding DNA to the Genealogist's Toolbox Sun, 05 May 2013 06:30:02 +0000 hourly 1 http://wordpress.org/?v=3.5.1 By: domas http://www.thegeneticgenealogist.com/2008/08/05/are-pathogenic-mtdna-mutations-common/comment-page-1/#comment-4378 domas Mon, 05 Oct 2009 17:08:36 +0000 http://www.thegeneticgenealogist.com/?p=543#comment-4378 Studies of oncocytic tumours have led to hypotheses which propose that defects in oxidative phosphorylation may result in a compensatory increase in mitochondrial replication and/or gene expression. Mutational analysis of mtDNA in thyroid neoplasia, which is characterised by increased numbers of mitochondria and is also one of the most common sites of oncocytic tumours. has been limited to date. Using the recently developed technique of two-dimensional gene scanning, we have successfully examined 21 cases of thyroid tumours, six cases of non-neoplastic thyroid pathology, 30 population controls, nine foetal thyroid tissues and nine foetal tissues of non-thyroid origin, either kidney or liver.

From: ncbi.nlm.nih.gov/pubmed/10803467

domas’s last blog post..Traces of inflammation in the blood increase the possibility of Alzheimer’s disease

]]>