Comments on: Tracing a 500-Year-Old Founder Mutation Using Genetic Genealogy

By: DeCodeMe Update

DeCodeMe Update — Tue, 19 Aug 2008 17:29:54 +0000

[...] here from Blaine Bettinger:Tracing a 500-Year-Old Founder Mutation Using Genetic Genealogyhttp://www.thegeneticgenealogist.com/2008/04/21/tracing-a-500-year-old-founder-mutation-using-geneti…"Software used by the researchers predicted that this mutation arose about 500 years ago (with [...]

By: n/a

n/a — Tue, 22 Apr 2008 00:52:59 +0000

I agree, it's mostly on the journalists, and the researchers qualified their theories appropriately. Still, I think failing to check England as a potential source (or explain why they didn't) was a major oversight. n/a's last blog post..Cherokee cancer gene? Not quite.

By: Blaine Bettinger

Blaine Bettinger — Tue, 22 Apr 2008 00:02:11 +0000

Terrific post and a very in-depth analysis. I have more of a problem with the journalists picking up and concentrating on this minor point than I do with the authors for hypothesizing.

By: n/a

n/a — Mon, 21 Apr 2008 23:52:42 +0000

I replied to this story here. Key point is I believe there is zero evidence in favor of a "Native American" source for the mutation. n/a's last blog post..Cherokee cancer gene? Not quite.

By: race/history/evolution notes

race/history/evolution notes — Thu, 01 Jan 1970 00:00:00 +0000

Rootsweb WorldConnect databases) and a copy of the paper are available here. Clendenning et al. Origins and Prevalence of the American Founder Mutation of MSH2. Cancer Research 68, 2145-2153, April 1, 2008. doi:0.1158/0008-5472.CAN-07-6599 (Story viaThe Genetic Genealogist.)

By: Daily Cells - Daily Top Blog Posts on Genetics - Powered by SocialRank

Daily Cells - Daily Top Blog Posts on Genetics - Powered by SocialRank — Thu, 01 Jan 1970 00:00:00 +0000

6.Tracing a 500-Year-Old Founder Mutation Using Genetic Genealogywww.thegeneticgenealogist.com4 commentsSocialRank In January I wrote about a study that traced a mutation in a single colon cancer gene to 1630. Today, researchers announced that a founder mutation in another gene, MSH2, has been traced to