The Web 2.0 Summit in San Francisco just ended.Â One of the first speakers was J. Craig Venter, whose genome was recently sequenced.Â He gave a lecture about personalized medicine, personal genetics, and his new book, “A Life Decoded: My Genome, My Life.”
Today’s issue of Science contains a new look into the world of genetic genealogy. “The Science and Business of Genetic Ancestry Testing“, led by researchers at the University of Texas at Austin, examines the benefits and drawbacks of genetic genealogy. Here is a table summary of the researcher’s conclusions:
Table from: â€œDeep Roots”â€ at www.utexas.edu/features/2007/ancestry/.
One interesting fact from the article is that the number of people who have purchased genetic genealogy tests is estimated to be over 460,000! If you would like to read more about this study, there are a number of other sources of information, including a press release from The University of Texas at Austin, where the first author, Deborah A. Bolnick, is assistant professor of anthropology. There is also a feature story at The University of Texas’ website. In this feature story, Dr. Bolnick states:
Genome Technology Online mentioned the new partnership between DNAPrint Genomics, Inc. and BioServe, a company that offers â€œthe Global RepositoryÂ®, a growing library of over 600,000 human DNA, tissue and serum samples linked to detailed clinical and demographic data from 140,000 consented and anonymized patients from four continents.â€
As part of the partnership, DNAPrint will analyze the 600,000 human samples in the Global Repository using the ANCESTRYbyDNA test.According to Richard Gabriel, the CEO and President of DNAPrint Genomics:
“By removing the question of ancestry from a clinical sample researchers can more readily evaluate which medicines will produce side effects within certain ethnic groups, and which medicines will work for the widest spectrum of a population.”
Tim Agazio at Genealogy Reviews Online presents the first post in a series that will review the genetic genealogy testing process at DNAAncestry. In this first installment, Tim discusses the website, the tests offered, and the ease of ordering.
I will actually be doing a similar review in the near future, as I’ve ordered a test from DNAAncestry for my maternal grandfather’s Y-chromosome. Since he unfortunately passed away in 1983, it will be a great opportunity to talk about finding other alternatives, finding other people with the same surname, and joining surname projects – in addition to other questions often asked about genetic genealogy. If there is anything you’d like me to highlight in this process, please leave a comment and I will do my best to address it!
One of the best things about this offering is the FIND tool. FIND is a way to identify the type of DNA test that best suits the customer’s need(s). Through a series of very simple questions that guide the user step-by-step, the tool helps him or her decide between ethnicity tests, Y-DNA tests, or mtDNA tests. I had fun just playing around with it.
The company also provides information about genetic genealogy, including “How DNA Reveals Ancestry,” “Who’s Using Ancestry & Ethnicity Tests,” and “DNA Testing Resources“, just to name a few. There are some great sources of information listed on the DNA Testing Resources page, and at least one AMAZING resource, if I do say so myself!
An article appearing Sunday at Bloomberg.com, “Cheap, Detailed Genetic Testing Might Soon Be Ready for Market“, highlights some of the recent developments in DNA sequencing. The article is a response to three studies published yesterday at Nature Methods (available here, here, and here) which reportedly “explore cheap technologies to decipher and analyze individual patients’ DNA by allowing researchers to quickly find the small portions of the human genome that make protein and describe them, while discarding irrelevant data.”
According to the author of the Bloomberg article, “complete” DNA sequencing for as little as $300 could be ready within months. Although it is unclear what the author means by “complete”, it is entirely foreseeable that SNP testing will soon be available for a reasonable price.
I was being completely serious yesterday. I can barely keep up with all the genetic genealogy in the news, so here’s yet another round-up of the all the latest:
Sorenson Genomics is everywhere in the news. For example, a recent article in the Daily Herald discusses Scott Woodward’s love of genetics. Woodward is the Director and Chief Scientific Officer of the Sorenson Molecular Genealogy Foundation. Megan Smolenyak wrote about this article at Megan’s Roots World. Sorenson also announced that it will merge the Identigene and GeneTree DNA testing units (HT: Genome Technology Online).
Jasia at Creative Gene discusses some of the financial costs associated with genetic genealogy. It appears that this will be a series of posts, and I’m very interested to see how the costs compare to traditional genealogical research. Note that Creative Gene is a member of The Genealogists, a Feedburner Network of some of today’s best genealogical blogs.
There is so much information about genetic genealogy in the news right now that I am having a hard time keeping up. That, of course, is good news. So here is a round-up of some of the best from the web:
“Seeking Columbus’s Origins, With a Swab” is an article in today’s New York Times (HT: Liz). Scientists and genetic genealogists hope to use Y-DNA to compare DNA that might be Columbus’s to modern-day people with a related surname.
“Genetic Genealogy Mildly Hot” is a post by Hsien at Eye On DNA that explains why “family tree dna” was one of the top 100 searches at Google Trends yesterday. Got a guess?
In “60 Minutes on DNA: Deja Vu All Over Again“, Megan Smolenyak looks at Sunday’s 60 Minutes segment about genetic genealogy. It’s a brilliant post, especially with the following sentence:
Did you catch the genetic genealogy segment on 60 Minutes last night? I was not able to watch it, unfortunately, but I’ve been following some online reactions. For instance, at Megan’s Roots World (written when the segment was being made), Anglo-Celtic Connections and DNA for Everyone. There’s a great discussion at the DNA-NEWBIE Yahoo Group, and at the GENEALOGY-DNA Rootsweb list.
For those who missed the segment last night, HERE is the full report, with a video and transcript. Note that the journalists interviewed Hank Greely, a law professor at Stanford who I’ve mentioned here before, and who has a great chapter in an upcoming book – Revisiting Race in a Genomic Age, (forthcoming) edited by Barbara Koenig, Sandra Soo-Jin Lee, and Sarah Richardson. Rutgers University Press, 2007.
The Scientist is attempting to compile the list of the most popular science blogs:
“We at The Scientist are asking you to help compile the first list of the best life science blogs. Tell us what your favorite life science blogs are and why by clicking the button and leaving a comment, and we will publish a list of the most popular choices across the different areas of life sciences. With your help we hope to provide a list of who is currently hot in the science blogosphere, and why you should be reading them.”
It’s not a popularity contest (oh wait, it is!), but if you think of any great science-related blogs (ahem), stop by and let them know!
And if you don’t feel like nominating anyone, just scroll through the list and click on some links!Â It’s a great way to discover new science blogs.