Comments on: DYS464 and Male Infertility

By: Myrtie Lassalle

Myrtie Lassalle — Thu, 14 Mar 2013 10:11:06 +0000

Approximately 2 million American women undergo some type of fertility treatment every year. Contrary to the intensive media coverage of fertility issues, infertility has not reached epidemic proportions. According to the National Center for Health Statistics, the number of infertile married couples was actually lower in 1995 2.1 million than in 1982 2.4 million.;Infertility rates have not increased in the past three decades, but treatment protocols were forever changed the moment Louise Brown entered the world in 1978.”

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By: Sarah

Sarah — Thu, 18 Nov 2010 12:12:16 +0000

Hello everyone – I hope this is a good place to say this given I am at my wits end. My name is Sarah and my husband and I have been trying (unsuccessfully) to conceive for almost four years now and have been through much together through our lives. I have experienced two miscarriages and several different doctors in an attempt to conceive our first child.

My husband is 31 and I am 29 years old and following my first signs of pregnancy which I identified really early at around 3 weeks, our baby unfortunately did not make it past the first month. In our second pregnancy, the hospital for some unknown reason did not take a blood test to verify the pregnancy. I was visited at home by the local nurse and on each occasion in light of our previous miscarriage I asked again for a blood test to confirm all was well.

Despite them not doing a blood test I insisted upon an ultrasound as I just had to know everything was ok – the ultrasound confirmed something I think we both already felt that the baby again didn’t make it. As you can imagine we were both devastated (again). The doctors told us I had a problem with my uterus, and the uterus walls were abnormally thick, which it was assumed was causing the problem – we were told to persevere…

So we continued to try and recently I fell pregnant for the third time. I experienced bleeding for almost 1 month straight and the doctors could not really give me any answers why I was bleeding and simply conducted routine blood work to ensure I wasn’t loosing too much blood and a brief check to look for any abnormalities. A little while later, you guessed it the baby passed. This time I was given more information from the doctors whom suggested there is the potential that my body does not produce sufficient amounts of the progesterone hormone to stay pregnant in addition to the thick wall of my uterus.

As you can imagine both my husband and I are exhausted and so want to have a baby but are determined – there are some procedures I can undergo apparently and also some drugs which can help with the hormone levels but I am really at my wits end. I regularly scour the internet looking for answers to my questions and recently came across this site (http://www.conceptionadvice.co.cc) which seems to show some good success stories, I will try anything at the moment, has anyone here heard about this or tried the course? I am running out of options (although we continue to try) and would appreciate any help anyone can provide to us.

By: Mesothelioma Awarene

Mesothelioma Awarene — Wed, 20 May 2009 11:57:24 +0000

Great! More and more research is needed to find better cure and causes of many diseases.

By: DYS464 and infertility/mt-H and protection from sepsis?? - Family Tree DNA Forum

DYS464 and infertility/mt-H and protection from sepsis?? - Family Tree DNA Forum — Fri, 16 Jan 2009 04:17:14 +0000

[...] means a lack of all of them. As they are a subgroup of one marker??? Here’s another website http://www.thegeneticgenealogist.com…e-infertility/ I wonder what my mtDNA would be…. guess I would need to test it. I wonder if its H. [...]

By: Are Pathogenic mtDNA Mutations Common? » The Genetic Genealogist

Are Pathogenic mtDNA Mutations Common? » The Genetic Genealogist — Tue, 05 Aug 2008 07:01:25 +0000

[...] genealogy has the potential to reveal information about your health (for example, DYS464 can reveal infertility and sequencing of the entire mtDNA genome can reveal mutations that are suspected of being [...]

By: Parallel Dataverses: Doppelgangers in Medicine and Recreation : The Personal Genome

Fri, 11 Jul 2008 21:13:39 +0000

[...] of genetic sequence data, which might include the discovery of a medically relevant genotype (e.g., male infertility and genealogy testing) and health insurance [...]

By: “One Package Fits All” DNA Testing

“One Package Fits All” DNA Testing — Fri, 04 Jan 2008 16:17:00 +0000

[...] summer, the DYS464 Y-DNA marker was found to be associated with spermatogenic failure and consequently, male infertility. The frequency of the specific AZFc deletion in the DYS464 [...]

By: Infertility Blog

Infertility Blog — Thu, 08 Nov 2007 22:54:57 +0000

[...] The Genetic Genealogist – " DYS464 and Male Infertility [...]

By: The Genetic Genealogist - » 10 DNA Testing Myths Busted

The Genetic Genealogist - » 10 DNA Testing Myths Busted — Thu, 25 Oct 2007 07:01:42 +0000

[...] It is important to note, however, that some medical information (such as infertility detected by DYS464 testing or other diseases detectable by a full mtDNA sequence) might inadvertently be revealed by a genetic [...]

By: ramunas

ramunas — Wed, 25 Jul 2007 21:41:59 +0000

hi. well, who knows – before 30 years idea about personal computer was ridiculous. And now there is personal DNA analyzer on the market already: http://cancergenetics.wordpress.com/2007/07/20/personalized-dna-analyser-precautions/
but maybe we do not need to amplify anything in a near future? – http://helicosbio.com/62BF65F522E048CEB03FAF69C4AB7B07.asp?ps_key=167F2249805D46CBBCFA9411F774CD4F&page=1&ie_key=1E21A8B7AC5043279851D73C51DC420B