The Genetic Genealogist has been invited to be a member of the new genetics blogging group The DNA Network
, founded by Rick Vidal of My Biotech Life
and Hsien Lei of Eye on DNA
. The group is “a network (double helix?) composed of life science enthusiasts with specialized views in areas such as genetics, biology, biotechnology, health care, and much more.”
Not only is the network a great way to discover new blogs, but it is an opportunity to stay current on events and developments in the field of genetics. The following blogs are currently members of the network:
My Biotech Life
DNA Direct Talk
Eye on DNA
Gene Sherpas: Personalized Medicine and You
henry: the human evolution news relay (genetics)
Mary Meets Dolly
Microarray and Bioinformatics
And me, The Genetic Genealogist.
Thomas Jefferson, 3rd President of the United States, has been at the center of a DNA controversy for over 200 years.In September 1802 journalist James T. Callender wrote in Richmond Reporter that Jefferson had for many years â€œkept, as his concubine, one of his slaves.Her name is Sally [Hemmings].The name of her eldest son is Tom.His features are said to bear a striking though sable resemblance to those of the president himself.â€Although these rumors had reportedly already been passed around quietly, this article spread the rumor far and wide, setting off many years of debate.
In 1998 analysis of a male descendant of Jeffersonâ€™s paternal uncle showed that Jeffersonâ€™ Y chromosome belonged to haplogroup K2 (Thomas Jefferson did not have any male descendants to provide DNA.For more information, see: â€œJefferson fathered slaveâ€™s last child.” 1998. Nature 396 (6706): 27â€“28. PMID 9817200).Haplogroup K2 is rather rare, constituting just 1% of worldwide Y chromosomes (See â€œThomas Jeffersonâ€™s Y chromosome belongs to a rare European lineage.â€ Am J Phys Anthropol 132(4): 584-9.PMID 17274013 ).Surprisingly, or perhaps not-so-surprisingly depending on which side of the debate you stood, a male descendant of Sally named Easton Hemmings possessed the same K2 chromosome, suggesting a genetic link between Jefferson and Easton.Keep in mind, however, that this is not determinative since it is possible that any of Jeffersonâ€™s male relatives (who possessed the same Y chromosome) could have fathered Easton.And keeping in mind that non-paternal events are ALWAYS a possibility, nothing is 100% certain.Not until we can time-travel and obtain DNA samples from the source!
Some scientists have hypothesized that Australian aboriginals received a portion of their DNA from an ancient hominid species called Homo erectus, which for a short time was contemporaneous with modern man. A recent study published in PNAS (Proceedings of the National Academy of the Sciences) set out to answer this question by analyzing mtDNA and Y-chromosome samples from aboriginals.
A total of 172 mtDNA and 522 Y-chromosome previously published and new sequences from aboriginal Australians and New Guineans were analyzed for mtDNA and Y-chromosome variation and were compared to the current world haplogroup tree. All of the mtDNA sequences were members of the M and N founder branches, and all of the Y-chromosome sequences fell into the C and F founder branches.
FamilySearch (a nonprofit organization sponsored by The Church of Jesus Christ of Latter-day Saints) announced today that it will provide FREE services to any and all archives and records custodians who wish to digitize, index, publish, and preserve their collections.This is, of course, on top of the ambitious project already underway to digitize and make freely available the 2 million rolls of microfilm stored in the Granite Mountain Records Vault.
This is a huge benefit for genealogists, since many more records will be freely available online.This is also a huge benefit for archivists and record depositories, since they can digitize and make available their collections for free using FamilySearchâ€™s many years of scanning experience.
I spent the morning doing a redesign of the blog.Â I should have been studying, but I’ve been meaning to give the site a new look for a while now.Â My goals were (1) to make the content the center of attention; (2) to quickly and easily provide information about the blog and subscription options to newcomers; (3) to minimize the impact of advertising (since I don’t make that much anyway!); and (4) to make the site more visually pleasing and professional.Â If you have any problems accessing information or using the site, please be sure to let me know.Â If you like the new design, let me know that too!
Do you have a burning question about genetics that’s been keeping you up at night? Ever wonder why the combination of red hair and brown eyes is so rare? There are two great resources currently available online for anyone who is curious about genetics.
AsktheGeneticist is a partnership between the Department of Human Genetics at Emory University and theDepartment of Genetics at the University of Alabama at Birmingham.The mission of AsktheGeneticist â€œis to answer questions about genetic concepts, and the etiology, treatment, research, testing, and predisposition to genetic disorders.â€ AsktheGeneticist has a genetic genealogy section, but itâ€™s pretty sparse.
The Tech Museum of Innovation in San Jose, California has partnered with the Department of Genetics at Stanford University to present â€œGenetics: Technology with a Twist.â€The interactive site has an â€˜Ask The Geneticistâ€™ section where you can ask a Stanford geneticist a question.
1.You got those big blue eyes from your grandmother, but chances are you inherited less desirable genes as well.We inherit our DNA from our parents, who inherited it from their parents.Since we all possess genes that can cause or contribute to disease, knowing oneâ€™s DNA and family medical history can be a great resource for someone who learns they have a genetic disorder.
2.Full genome sequencing is right around the corner!The X-prize quest for the $1000 genome will lead to efficient and affordable whole-genome sequencing.As commercial companies crop up and compete for customerâ€™s business, leading to even lower prices.
3.Your grandmotherâ€™s DNA contains clues to her ancestry.X-chromosome, mtDNA, and autosomal genealogy tests contain clues to a personâ€™s ancestry, both recent and ancient.
I just wanted to let my readers know that posting will be on the light side this week because of exams.Â Â I am finishing up my first year of law school, so Constitutional law and Property are taking up most of my time.Â And stay tuned, I have some big projects in the works for the very near future!
Scienceroll just posted a hilarious video called the “DNA-ting Game“, an advertisement for Caliper Life Sciences which is a spoof on 1970’s “The Dating Game.” If you think science humor is funny, you’ll love this video. I highly recommend you go check it out. For a little background information, they talking about analyzing DNA samples using gel electrophoresis. The video is actually an elaborate advertisement for an alternative to electorphoresis.
There are some other funny videos I’ve seen as well, including the great advertising campaign from Biocompare. There are three commercials – here, here, and here. They’re another example of biotechnology companies jumping into this field of advertising. In our lab we typically made decisions based on price, but who knows what effect appealing to our sense of humor might have?
I was very surprised when genetic testing revealed that my maternal lineage was not European. I’m sure, however, that my surprise was nothing compared to that of two British women who recently discovered that their maternal lineage was of Native American descent (the original article is available through the BBC).
Doreen Isherwood and Anne Hall learned that their mtDNA belonged to Haplogroups A and C, traditional Native American Haplogroups. As the BBC story explains, Native Americans were brought back to England as early as the 1500s.
Said Ms. Hall: “I was thrilled to bits. It was a very pleasant surprise. To have Native American blood is very exotic.”
Thanks to The Genealogue.