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MITOMAP Publishes an Updated mtDNA Phylogenetic Tree

MITOMAP, the human mitochondrial genome database, has recently published a paper in Nucleic Acids Research (Free Full Text Here) announcing the completion of a full human mtDNA phylogenetic tree.

This tree, available here(pdf) was constructed from 2959 mtDNA coding region sequences (using the rCRS as the reference). In addition to listing mutations and the study that identified each particular sequence, the tree labels each mutation as a substitution mutation, a silent mutation, a tRNA or rRNA mutation, a mutation in the noncoding region, or a pathological mutation. MITOMAP also provides another valuable tool, tables of mtDNA polymorphisms with source information.

The tree will potentially be very useful to both researchers and genetic genealogists by providing a quick and easy way to characterize new sequences. Anyone interested in learning more about their haplogroup or how their haplogroup fits into the human mtDNA tree will find the new mtDNA phylogenetic tree extremely informative.

Blaine Bettinger

Intellectual property attorney, genealogist, and author of The Genetic Genealogist since 2007