AncestryByDNA is a popular genetic test developed by DNAPrint Genomics, Inc. The company offers a variety of genetic testing, including Y-chromosome and mtDNA ancestry. They are most well-known, however, for their two admixture tests. Admixture tests examine SNPs, or single nucleotide polymorphisms, in the 22 autosomal chromosomes in each of our cells. Although every humanâ€™s DNA is 99.9% identical, the 0.1% differences make each one of us unique. Researchers have noticed that people in a particular region often have a mutation in common, one that people in most or all other regions of the world do not have. These usually harmless mutations, called SNPs, are believed to have bio-geographic properties â€“ people endogenous to certain regions of the world … Click to read more!
How many founding Asian groups braved their way across the Bering land bridge during those frigid Pleistocene ice ages? Was it a single wave of people who later developed into the three distinct linguistic and cultural groups that populated the Americas, or were there multiple waves of people each with their own language and culture? Or was it some mix of the two? The issue has been and continues to be a topic of debate.
Linguistic studies of the Na-dene, Aleut-Eskimo, and Amerind language groups suggested that there were three waves across the land bridge, one for each language group. Recent genetic research, however, has suggested that there was only a single wave of founding groups into the Americas. (Read a free online review … Click to read more!
With the arrival of Black History Month and following on the heels of PBSâ€™s popular series â€˜African American Livesâ€™, increasing numbers of African Americans are deciding to explore the world of DNA testing and genetic genealogy. As a result many newspapers and magazines are taking the opportunity to introduce their readers to this increasingly popular avenue of genealogical research.
The Rocky Mountain News in Denver, Colorado is currently three articles into a six-part series examining the role and effect of genetic genealogy in African American research [Thanks to Genealogy Reviews Online]:
Saturday, 17 February 2007 (Two articles, here and here).
Monday, 19 February 2007
Tuesday, 20 February 2007
Wednesday, 21 February 2007
Thursday, 22 February 2007
Friday, 23 February 2007
Fortune Magazine published an article, â€˜Tracing African Roots Through DNAâ€™, on February 16th in which the … Click to read more!
Genealogists interested in researching their Scottish roots will soon have a new resource thanks to a new genealogy center created by the
This testing will be done by mouth swab and will be conducted in a new forensics lab built at the University.Â The center will use both Y-chromosome and mtDNA results to build their database.Â Researchers at the University hope that the center will eventually be able to build a genetic map of the … Click to read more!
African Ancestry has had a very good year.Â The popular PBS series â€˜African American Livesâ€™, which analyzed the African roots of nine famous figures (such as Oprah, Quincy Jones, Whoopi Goldberg, Chris Tucker, and Dr. Sara Lawrence-Lightfoot), used the African Lineage Database developed by the Scientific Director of African Ancestry, Dr. Rick Kittles.Â This publicity has resulted in African Ancestry being featured in a wide array of newspaper and magazine articles around the world.
African Ancestry offers two types of DNA analysis, the Matriclan test and the Patriclan test.Â The Matriclan test sequences a portion of an individualâ€™s mtDNA to determine whether the ancestry of that lineage is African, European, or other ethnic … Click to read more!
Researchers have analyzed the (abstract here) HVR1 (hypervariable region 1) of the mtDNA control region belonging to an ancient female skeleton.Â The skeleton, approximately 3,600 years old, was discovered in 1980 in a frozen Neolithic grave in northeastern Siberia.
Sequencing of a 377-base pair fragment (16015-16391) revealed three mutations; C16223T, T16298C, and C16327T.Â These mutations are characteristic of haplogroup C in Siberian and Asian … Click to read more!
A recent study by has characterized an allele that is present in all Native American populations tested. The allele, 9RA (9 repeat-allele) is a 9 tetranucleotide repeat allele composed of 275 bp at autosomal (meaning non-sex chromosome) microsatellite locus D9S1120 (on chromosome 9). Microsatellites are small DNA repeats that are typically neutral and are often used as molecular markers for population studies. According to the report, 9RA was found at an average percentage of roughly 30% among all the populations.
Although 9RA was found among Chukchi and the Koryaks of Western Beringia (on the eastern edge of Siberia), the allele was not identified in the large number of Asian populations tested (perhaps because this is a mutation that arose in populations as they approached the land bridge or because … Click to read more!
Sciona, Inc., a Boulder, Colorado company that sells personalized genetic tests for lifestyle counseling based on an individualâ€™s diet, exercise, lifestyle, and genetic screening, has recently launched the website MyCellf to explore the growing field of nutritional genomics. Nutrigenomics is the study of the interaction between genes and diet.
According to a recent press release, MyCellf is designed to:
â€œprovide a balance between information, customer interaction and commerce for interested consumers and healthcare professionals. The company offers a unique non-medical, lifestyle counseling based on an individual’s diet, exercise and lifestyle history and a confidential genetic screening. By supplying this information direct to consumers through a … Click to read more!
I recently highlighted an article published in the American Journal of Physical Anthropology entitled “Genetic analysis of early holocene skeletal remains from Alaska and its implications for the settlement of the America”.
I thought it might be interesting to ask one of the authors, Dr. Brian M. Kemp, his thoughts on the relationship between genetic genealogy and anthropological research, the future of Native American anthropology, and how he entered the field. Dr. Kemp, who is currently doing a post-doc at Vanderbilt University, was kind enough to share some of his valuable time.
Will genetic testing of the public through companies such as Family Tree DNA and Oxford Ancestors have any impact on the study of anthropology?
“Well, it certainly places … Click to read more!
23andMe is a startup company in California that describes themselves as “an early startup developing tools and producing content to help people make sense of their genetic information. Our goal is to take advantage of new genotyping technologies and help consumers explore their genetics, informed by cutting edge science.”
What are the goals of 23andMe? The website claims that a person’s personal genetic information “will provide personal insight into ancestry, genealogy and health. For society, the collection of genotypic and phenotypic information on a large scale will provide scientists with novel avenues for research. “It should also be noted that 23andMe has ‘strong financial backers” and is looking for “talented, motivated individuals in many areas who have a passion … Click to read more!